Improving Growth, Digestive and Antioxidant Enzymes and Immune Response of Juvenile Grass Carp (Ctenopharyngodon idella) by Using Dietary Spirulina platensis

The present study was designed to investigate the effect of Spirulina platensis (SP) supplemented diets on growth performance, digestive enzymes, hepatic antioxidants and innate immunity biomarkers in juvenile grass carp (Ctenopharyngodon idella). Two hundred forty juveniles (average weight 4.81 ± 0.13 g) were divided into four treatment groups triplicates (20 fish/replicate) fed with containing 0, 1, 5, 10% for 90 days. A significant increase (p < 0.05) observed fish having 1 5% Spirulina. Intestinal protease lipase activities increased significantly 0.01) a diet while intestinal amylase activity Hepatic lipid peroxidation decreased diet. catalase, glutathione-S-transferase, glutathione levels livers 1% no difference > superoxide dismutase when compared control. Significant increases skin mucus 0.05), antiprotease 0.01), lysozyme 0.001), peroxidase Spirulina-supplemented diets. Gene expression analysis head kidney showed that had higher tnf-?, il-8, inf-?. In conclusion, suggested inclusion has positive effects growth, antioxidants, immunity.